The Regional Center for Social Science and Sustainable Development (RCSD), Faculty of Social Sciences at Chiang Mai University has a long history of engagement in knowledge production on social transformation in the Mekong sub-region, and its impacts on local communities since 1998. It has supported an international graduate program aiming to cultivate social science education for students from neighbouring countries and beyond, as well as cooperated with international researchers in doing research on emerging issues related to resource governance, ethnic politics, cross-border migration, agrarian and local livelihood change, etc. It has carried out Chiang Mai University’s internationalization policy by organizing several international conferences, such as, International Conference on Thai Studies (ICTS13) and International Convention for Asian Scholars (ICAS10) in 2017. RCSD has developed capacity building programme at National University of Laos and Capacity Building Program for Teaching and Research at University of Mandalay. RCSD played a crucial role in organizing International Conference on Burma/Myanmar Studies in 2015, 2018 and 2021, providing an opportunity for scholars, students and civil society actors Myanmar to exchange and sharing knowledge with their Thai and international counterparts. RCSD’s expertise and experience enable us to lead the field research implementation, contribute our local knowledge and established connections to communities and the local administration, facilitate research approvals, provide workspace in an interdisciplinary and stimulating research environment, manage the research grant and human resources locally, and link the project to policy stakeholders in Chiang Mai, Thailand, and the greater Mekong region.